Aditi Bhattacharya and Eric Klann
http://learnmem.cshlp.org/content/19/9/434.long
Persons with pervasive developmental disorders (PDD) exhibit a range of cognitive deficits that hamper their quality of life, including difficulties involving communication, sociability, and perspective-taking. In recent years, a va...
The molecular basis of cognitive deficits in pervasive developmental disorders.
October 2, 2012
Glucagon-Like Peptide-1 Cleavage Product GLP-1(9-36) Amide Rescues Synaptic Plasticity and Memory Deficits in Alzheimer’s Disease Model Mice.
October 5, 2012
Multiple Components of eIF4F are Required for Protein Synthesis-dependent Hippocampal Long-term Potentiation.
October 22, 2012
Genetic Removal of p70 S6 Kinase 1 Corrects Molecular, Synaptic, and Behavioral Phenotypes in Fragile X Syndrome Mice
October 22, 2012
Neuronal Expression of the Ubiquitin E3 ligase APC/C-Cdh1 During Development is Required for Long-term Potentiation, Behavioral Flexibility, and Extinction
December 18, 2012
The E3 ligase APC/C-Cdh1 is required for associative fear memory and long-term potentiation in the amygdala of adult mice
December 18, 2012
Exaggerated translation causes synaptic and behavioural aberrations associated with autism
December 26, 2012
The translation of translational control by FMRP: therapeutic targets for FXS
April 18, 2013
Jennifer C. Darnell, and Eric Klann
http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.3379.html
De novo protein synthesis is necessary for long-lasting modifications in synaptic strength and dendritic spine dynamics that underlie cognition. Fragile X syndrome (FXS), characterized by intellectual disability...
Translational control by eIF2α kinases in long-lasting synaptic plasticity and long-term memory
June 7, 2013
Genetic Reduction of the alpha-1 Subunit of Na/K-ATPase Corrects Multiple Hippocampal Phenotypes in Angelman Syndrome
August 2, 2013