Charles. A. Hoeffer, Emanuela Santini, Tao Ma, Elizabeth C. Arnold, Ashley M. Whelan, Helen Wong, Philip Pierre, Jerry Pelletier, and Eric Klann
http://jn.physiology.org/content/early/2012/10/05/jn.00342.2012.long
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Multiple Components of eIF4F are Required for Protein Synthesis-dependent Hippocampal Long-term Potentiation.
October 22, 2012
Genetic Removal of p70 S6 Kinase 1 Corrects Molecular, Synaptic, and Behavioral Phenotypes in Fragile X Syndrome Mice
October 22, 2012
Aditi Bhattacharya, Hanoch Kaphzan, Amanda C. Alvarez-Dieppa, Jacyln P. Murphy, Philippe Pierre, and Eric Klann
http://www.cell.com/neuron/abstract/S0896-6273(12)00673-3?switch=standard
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Exaggerated translation causes synaptic and behavioural aberrations associated with autism
December 26, 2012
Emanuela Santini, Thu N. Huynh, Andrew F. Macaskill, Adam G. Carter, Philippe Pierre, Davide Ruggero, Hanoch Kaphzan, and Eric Klann
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11782.html
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The translation of translational control by FMRP: therapeutic targets for FXS
April 18, 2013
Jennifer C. Darnell, and Eric Klann
http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.3379.html
De novo protein synthesis is necessary for long-lasting modifications in synaptic strength and dendritic spine dynamics that underlie cognition. Fragile X syndrome (FXS), characterized by intellectual disability...
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Translational control by eIF2α kinases in long-lasting synaptic plasticity and long-term memory
June 7, 2013
Mimi A. Trinh, and Eric Klann.
http://www.sciencedirect.com/science/article/pii/S1074742713000713
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Antipsychotics activate mTORC1-dependent translation to enhance neuronal morphological complexity
May 5, 2014
Heather Bowling, Guoan Zhang, Aditi Bhattacharya, Luis M. Pérez-Cuesta, Katrin Deinhardt, Charles A. Hoeffer, Thomas A. Neubert, Wen-biao Gan, Eric Klann, and Moses V. Chao
http://www.ncbi.nlm.nih.gov/pubmed/24425786...
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Mechanisms of translation control underlying long-lasting synaptic plasticity and the consolidation of long-term memory.
May 5, 2014
Emanuela Santini, Thu N. Huynh, and Eric Klann
http://www.ncbi.nlm.nih.gov/pubmed/24484700
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The eIF2α kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression.
May 5, 2014
Mimi A. Trinh, Tao Ma, Hanoch Kaphzan, Aditi Bhattacharya, Marcia D. Antion, Douglas R. Cavener, Charles A. Hoeffer, and Eric Klann
http://www.ncbi.nlm.nih.gov/pubmed/24741110
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Requirement of Mammalian target of rapamycin complex 1 downstream effectors in cued fear memory reconsolidation and its persistence.
July 7, 2014
Thu Huynh, Emanuela Santini, and Eric Klann
http://www.ncbi.nlm.nih.gov/pubmed/24990923
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Inhibition of AMP-Activated Protein Kinase Signaling Alleviates Impairments in Hippocampal Synaptic Plasticity Induced by Amyloid beta.
October 1, 2014
Tao Ma, Yiran Chen, Valarie Vingtdeux, Haitan Zhao, Benoit Viollet, Philippe Marambaud, and Eric Klann.
http://www.ncbi.nlm.nih.gov/pubmed/25186765
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