Multiple Components of eIF4F are Required for Protein Synthesis-dependent Hippocampal Long-term Potentiation.

October 22, 2012

Charles. A. Hoeffer, Emanuela Santini, Tao Ma, Elizabeth C. Arnold, Ashley M. Whelan, Helen Wong, Philip Pierre, Jerry Pelletier, and Eric Klann http://jn.physiology.org/content/early/2012/10/05/jn.00342.2012.long ...
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Genetic Removal of p70 S6 Kinase 1 Corrects Molecular, Synaptic, and Behavioral Phenotypes in Fragile X Syndrome Mice

October 22, 2012

Aditi Bhattacharya, Hanoch Kaphzan, Amanda C. Alvarez-Dieppa, Jacyln P. Murphy, Philippe Pierre, and Eric Klann http://www.cell.com/neuron/abstract/S0896-6273(12)00673-3?switch=standard ...
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Exaggerated translation causes synaptic and behavioural aberrations associated with autism

December 26, 2012

Emanuela Santini, Thu N. Huynh, Andrew F. Macaskill, Adam G. Carter, Philippe Pierre, Davide Ruggero, Hanoch Kaphzan, and Eric Klann http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11782.html ...
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The translation of translational control by FMRP: therapeutic targets for FXS

April 18, 2013

Jennifer C. Darnell, and Eric Klann http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.3379.html De novo protein synthesis is necessary for long-lasting modifications in synaptic strength and dendritic spine dynamics that underlie cognition. Fragile X syndrome (FXS), characterized by intellectual disability...
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Translational control by eIF2α kinases in long-lasting synaptic plasticity and long-term memory

June 7, 2013

Mimi A. Trinh, and Eric Klann. http://www.sciencedirect.com/science/article/pii/S1074742713000713 ...
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Antipsychotics activate mTORC1-dependent translation to enhance neuronal morphological complexity

May 5, 2014

Heather Bowling, Guoan Zhang, Aditi Bhattacharya, Luis M. Pérez-Cuesta, Katrin Deinhardt, Charles A. Hoeffer, Thomas A. Neubert, Wen-biao Gan, Eric Klann, and Moses V. Chao http://www.ncbi.nlm.nih.gov/pubmed/24425786...
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Mechanisms of translation control underlying long-lasting synaptic plasticity and the consolidation of long-term memory.

May 5, 2014

Emanuela Santini, Thu N. Huynh, and Eric Klann http://www.ncbi.nlm.nih.gov/pubmed/24484700 ...
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The eIF2α kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression.

May 5, 2014

Mimi A. Trinh, Tao Ma, Hanoch Kaphzan, Aditi Bhattacharya, Marcia D. Antion, Douglas R. Cavener, Charles A. Hoeffer, and Eric Klann http://www.ncbi.nlm.nih.gov/pubmed/24741110 ...
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Requirement of Mammalian target of rapamycin complex 1 downstream effectors in cued fear memory reconsolidation and its persistence.

July 7, 2014

Thu Huynh, Emanuela Santini, and Eric Klann http://www.ncbi.nlm.nih.gov/pubmed/24990923 ...
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Inhibition of AMP-Activated Protein Kinase Signaling Alleviates Impairments in Hippocampal Synaptic Plasticity Induced by Amyloid beta.

October 1, 2014

Tao Ma, Yiran Chen, Valarie Vingtdeux, Haitan Zhao, Benoit Viollet, Philippe Marambaud, and Eric Klann. http://www.ncbi.nlm.nih.gov/pubmed/25186765 ...
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