Fragile X syndrome therapeutics S(C)TEP through the developmental window

May 31, 2012
Aditi Bhattacharya and Eric Klann ...
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Genetic Removal of p70 S6 Kinase 1 Corrects Molecular, Synaptic, and Behavioral Phenotypes in Fragile X Syndrome Mice

October 22, 2012
Aditi Bhattacharya, Hanoch Kaphzan, Amanda C. Alvarez-Dieppa, Jacyln P. Murphy, Philippe Pierre, and Eric Klann ...
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The translation of translational control by FMRP: therapeutic targets for FXS

April 18, 2013
Jennifer C. Darnell, and Eric Klann De novo protein synthesis is necessary for long-lasting modifications in synaptic strength and dendritic spine dynamics that underlie cognition. Fragile X syndrome (FXS), characterized by intellectual disability...
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(Li+)ghting the way for a treatment for cognitive impairments in fragile X syndrome

May 5, 2014
Aditi Bhattacharya and Eric Klann  ...
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Dysregulation and restoration of translational homeostasis in fragile X syndrome.

October 8, 2015
Joel D. Richter, Gary J. Bassell & Eric Klann ...
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Aditi Bhattacharya and Eric Klann