Klann LAB Projects

  • Translational Control Of Learning and Memory

    Mechanisms of translational control in synaptic plasticity and cognitive function

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  • Fragile X Syndrome

    Cellular and molecular basis of synaptic dysfunction and aberrant behavior in FXS

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  • Neurodevelopmental Disorders

    Cellular and molecular basis of synaptic dysfunction and aberrant behavior in autism, tuberous sclerosis complex, and Angelman syndrome

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  • Aging and Alzheimer’s Disease

    Cellular and molecular basis of synaptic failure and memory impairments in aging and AD

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  • Development of Innovative Tools to Investigate Translation in the Nervous System

    Generation of mouse models for cell type-specific manipulation of translation, tools to visualize de novo protein synthesis, and techniques to identify translating mRNAs and newly synthesized proteins

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